1. Computational design of high-density oligonucleotide arrays for any organism: Oligonucleotide arrays are used in studying of gene expression and transcription in organism. Algorithm development is critical for enabling custom design of high-density oligonucleotide arrays for complex genomes, including the human genome.

2. Implementation of nanopore signal acquisition software: The ability to detect and record signals from single molecules of biological polymers during translocation through a nanopore is a critical component of the nanopore sensor. Sampling rates require integration of several high-speed acquisition hardware components. Data acquisition system should be able to detect event of DNA-translocation, acquire the signal data, and transfer the data from signal acquisition device to store in database automatically. This system will extract significant information from the electronic properties of subunits of DNA and RNA. It may be possible to obtain the linear composition of genetic polymer molecules.